Genetics of temporal lobe epilepsy

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چکیده

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Genetics of temporal lobe epilepsy.

I n the second half of the 19th century, John Hughlings Jackson proposed the concept of partial epilepsy, including ‘‘uncinate seizures’’, based on clinicopathological observations from patients with structural lesions and further supported by pioneering brain surgery. 2 With the discovery of EEG in the early 20th century, the concepts of temporal lobe epilepsy (TLE) were further elucidated. Gi...

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Genetics of Temporal Lobe Epilepsy: A Review

Temporal lobe epilepsy (TLE) is usually regarded as a polygenic and complex disorder. To understand its genetic component, numerous linkage analyses of familial forms and association studies of cases versus controls have been conducted since the middle of the nineties. The present paper lists genetic findings for TLE from the initial segregation analysis to the most recent results published in ...

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P8: Temporal Lobe Epilepsy and Mitochondrial Dysfunction

لطفاً به چکیده انگلیسی مراجعه شود.

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Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

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Endoscopic Transsphenoidal Resection of a Medial Temporal Arachnoid Cyst in a Patient with Temporal Lobe Epilepsy

Abstract Introduction: Arachnoid cysts are developmental cystic lesions which may be found as an incidental finding on neuroimaging or present with symptoms of headache, seizure and neurologic deficit. Presentation with seizure is more common with larger sizes and temporal location. Presentation with TLE is rare, and fenestration of cysts had variable results for seizure control. Here in, we r...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2003

ISSN: 0022-3050

DOI: 10.1136/jnnp.74.10.1359